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Importance of CD200 expression by tumor or host cells to regulation of immunotherapy in a mouse breast cancer model

Cell-surface CD200 expression by mouse EMT6 breast tumor cells increased primary tumor growth and metastasis to the draining lymph nodes (DLN) in normal (WT) BALB/c female recipients, while lack of CD200R1 expression in a CD200R1(-/-) host negated this effect. Silencing CD200 expression in EMT6(siCD...

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Publicat a:PLoS One
Autors principals: Curry, Anna, Khatri, Ismat, Kos, Olha, Zhu, Fang, Gorczynski, Reginald
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325206/
https://ncbi.nlm.nih.gov/pubmed/28234914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171586
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