Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis

Antiviral defenses are inappropriately activated in systemic lupus erythematosus (SLE) and association between SLE and the antiviral helicase gene, IFIH1, is well established. We sought to extend the previously reported association of pathogenic soluble mediators and autoantibodies with mouse Mda5 t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Munroe, Melissa E., Pezant, Nathan, Brown, Michael A., Fife, Dustin A., Guthridge, Joel M., Kelly, Jennifer A., Wiley, Graham, Gaffney, Patrick M., James, Judith A., Montgomery, Courtney G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325200/
https://ncbi.nlm.nih.gov/pubmed/28234905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171193
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