The effect of CYP2C9 and VKORC1 genetic polymorphisms on warfarin dose requirements in a pediatric population

OBJECTIVE: The aim was to investigate the frequency of genetic polymorphisms of cytochrome P4502C9 (CYP2C9) and vitamin K epoxide reductase complex subunit1 (VKORC1) and determine the effect of these polymorphisms on warfarin dose requirements in pediatric patients. METHODS: Fifty-eight pediatric pa...

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Vydáno v:Anatol J Cardiol
Hlavní autoři: Taşkın, Birce Dilge, Kula, Serdar, Ergün, Mehmet Ali, Altun, Demet, Olguntürk, Rana, Tunaoğlu, Fatma Sedef, Oğuz, Ayşe Deniz, Gürsel, Türkiz
Médium: Artigo
Jazyk:Inglês
Vydáno: Kare Publishing 2016
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324942/
https://ncbi.nlm.nih.gov/pubmed/27182616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14744/AnatolJCardiol.2015.6150
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