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Autophagy and KRT8/keratin 8 protect degeneration of retinal pigment epithelium under oxidative stress

Contribution of autophagy and regulation of related proteins to the degeneration of retinal pigment epithelium (RPE) in age-related macular degeneration (AMD) remain unknown. We report that upregulation of KRT8 (keratin 8) as well as its phosphorylation are accompanied with autophagy and attenuated...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Baek, Ahruem, Yoon, Soojin, Kim, Jean, Baek, Yu Mi, Park, Hanna, Lim, Daehan, Chung, Hyewon, Kim, Dong-Eun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324842/
https://ncbi.nlm.nih.gov/pubmed/28045574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1256932
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