Flexible and Scalable Full‐Length CYP2D6 Long Amplicon PacBio Sequencing

Cytochrome P450 2D6 (CYP2D6) is among the most important genes involved in drug metabolism. Specific variants are associated with changes in the enzyme's amount and activity. Multiple technologies exist to determine these variants, like the AmpliChip CYP450 test, Taqman qPCR, or Second‐Generati...

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Detalles Bibliográficos
Publicado en:Hum Mutat
Main Authors: Buermans, Henk P.J., Vossen, Rolf H.A.M., Anvar, Seyed Yahya, Allard, William G., Guchelaar, Henk‐Jan, White, Stefan J., den Dunnen, Johan T., Swen, Jesse J., van der Straaten, Tahar
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324676/
https://ncbi.nlm.nih.gov/pubmed/28044414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23166
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