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Sample size determination for a binary response in a superiority clinical trial using a hybrid classical and Bayesian procedure

BACKGROUND: When designing studies that have a binary outcome as the primary endpoint, the hypothesized proportion of patients in each population experiencing the endpoint of interest (i.e., π (1),π (2)) plays an important role in sample size and power calculations. Point estimates for π (1) and π (...

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Bibliografiske detaljer
Udgivet i:Trials
Main Authors: Ciarleglio, Maria M., Arendt, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324236/
https://ncbi.nlm.nih.gov/pubmed/28231813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-1791-0
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