High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with aP2-Cre-mediated Deletion of Estrogen Receptor Alpha

Estrogen receptor alpha (ERα) is a major regulator of metabolic processes in obesity. In this study we aimed to define the relevance of adipose tissue ERα during high-fat diet (HFD)-induced obesity using female aP2-Cre(−/+)/ERα(fl/fl) mice (atERαKO). HFD did not affect body weight or glucose metabol...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ban, Zsofia, Maurischat, Paul, Benz, Verena, Brix, Sarah, Sonnenburg, Anna, Schuler, Gerhard, Klopfleisch, Robert, Rothe, Michael, Gustafsson, Jan-Åke, Foryst-Ludwig, Anna, Kintscher, Ulrich
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324142/
https://ncbi.nlm.nih.gov/pubmed/28233809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43269
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