High expression of PDGFR-β in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence

Due to a lack of sufficient diagnostic tools to predict aggressive disease, there is a significant overtreatment of patients with prostate cancer. Platelet derived growth factors (PDGFs) and their receptors (PDGFRs) are key regulators of mesenchymal cells in the tumor microenvironment, and has been...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nordby, Yngve, Richardsen, Elin, Rakaee, Mehrdad, Ness, Nora, Donnem, Tom, Patel, Hiten R. H., Busund, Lill-Tove, Bremnes, Roy M., Andersen, Sigve
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324133/
https://ncbi.nlm.nih.gov/pubmed/28233816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43378
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