Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry

[Image: see text] The microsolvated state of a molecule, represented by its interactions with only a small number of solvent molecules, can play a key role in determining the observable bulk properties of the molecule. This is especially true in cases where strong local hydrogen bonding exists betwe...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Liu, Chang, Le Blanc, J. C. Yves, Schneider, Bradley B., Shields, Jefry, Federico, James J., Zhang, Hui, Stroh, Justin G., Kauffman, Gregory W., Kung, Daniel W., Ieritano, Christian, Shepherdson, Evan, Verbuyst, Mitch, Melo, Luke, Hasan, Moaraj, Naser, Dalia, Janiszewski, John S., Hopkins, W. Scott, Campbell, J. Larry
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324087/
https://ncbi.nlm.nih.gov/pubmed/28280776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00297
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