Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model

Cultures of epithelial cells are limited by the proliferative capacity of primary cells and cell senescence. Herein we show that primary human epithelial cell sheets cultured without dermal equivalents maintained homeostasis in vitro for at least 1 year. Transparency of these sheets enabled live obs...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Miyashita, Hideyuki, Niwano, Hiroko, Yoshida, Satoru, Hatou, Shin, Inagaki, Emi, Tsubota, Kazuo, Shimmura, Shigeto
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324070/
https://ncbi.nlm.nih.gov/pubmed/28233843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43557
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