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Computational methods using genome-wide association studies to predict radiotherapy complications and to identify correlative molecular processes

The biological cause of clinically observed variability of normal tissue damage following radiotherapy is poorly understood. We hypothesized that machine/statistical learning methods using single nucleotide polymorphism (SNP)-based genome-wide association studies (GWAS) would identify groups of pati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oh, Jung Hun, Kerns, Sarah, Ostrer, Harry, Powell, Simon N., Rosenstein, Barry, Deasy, Joseph O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324069/
https://ncbi.nlm.nih.gov/pubmed/28233873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43381
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