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Epidermolysis bullosa simplex in sibling Eurasier dogs is caused by a PLEC non-sense variant
BACKGROUND: Plectin, a large linker protein found in many tissues, acts to connect components of the cytoskeleton to each other. In the epidermis, plectin binds keratin intermediate filaments to hemidesmosomes. A deficiency of plectin in the skin leads to blister formation in the basal layer and the...
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| Veröffentlicht in: | Vet Dermatol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324056/ https://ncbi.nlm.nih.gov/pubmed/27878870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vde.12394 |
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