Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages

Noroviruses are understudied because these important enteric pathogens have not been cultured to date. We found that the norovirus murine norovirus 1 (MNV-1) infects macrophage-like cells in vivo and replicates in cultured primary dendritic cells and macrophages. MNV-1 growth was inhibited by the in...

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Hauptverfasser: Wobus, Christiane E, Karst, Stephanie M, Thackray, Larissa B, Chang, Kyeong-Ok, Sosnovtsev, Stanislav V, Belliot, Gaël, Krug, Anne, Mackenzie, Jason M, Green, Kim Y, Virgin, Herbert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2004
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC532393/
https://ncbi.nlm.nih.gov/pubmed/15562321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020432
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