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Macrophages of genetically characterized familial hypercholesterolaemia patients show up‐regulation of LDL‐receptor‐related proteins

Familial hypercholesterolaemia (FH) is a major risk for premature coronary heart disease due to severe long‐life exposure to high LDL levels. Accumulation of LDL in the vascular wall triggers atherosclerosis with activation of the innate immunity system. Here, we have investigated (i) gene expressio...

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Podrobná bibliografie
Vydáno v:J Cell Mol Med
Hlavní autoři: Escate, Rafael, Padro, Teresa, Borrell‐Pages, Maria, Suades, Rosa, Aledo, Rosa, Mata, Pedro, Badimon, Lina
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323824/
https://ncbi.nlm.nih.gov/pubmed/27680891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12993
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