Polymorphisms in drug-metabolizing enzymes and steady-state exemestane concentration in post-menopausal patients with breast cancer

Discovery of clinical and genetic predictors of exemestane pharmacokinetics was attempted in 246 post-menopausal patients with breast cancer enrolled on a prospective clinical study. A sample was collected two hours after exemestane dosing at a 1 or 3 month study visit to measure drug concentration....

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Vydáno v:Pharmacogenomics J
Hlavní autoři: Hertz, Daniel L., Kidwell, Kelley M., Seewald, Nicholas J., Gersch, Christina L., Desta, Zeruesenay, Flockhart, David A, Storniolo, Ana-Maria, Stearns, Vered, Skaar, Todd C, Hayes, Daniel F, Henry, N. Lynn, Rae, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323433/
https://ncbi.nlm.nih.gov/pubmed/27549341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2016.60
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