Sialylation transmogrifies human breast and pancreatic cancer cells into 3D multicellular tumor spheroids using cyclic RGD-peptide induced self-assembly

Multicellular tumor spheroids (MTS) have been at the forefront of cancer research, designed to mimic tumor-like developmental patterns in vitro. Tumor growth in vivo is highly influenced by aberrant cell surface-specific sialoglycan structures on glycoproteins. Aberrant sialoglycan patterns that fac...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Akasov, Roman, Haq, Sabah, Haxho, Fiona, Samuel, Vanessa, Burov, Sergey V., Markvicheva, Elena, Neufeld, Ronald J., Szewczuk, Myron R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323220/
https://ncbi.nlm.nih.gov/pubmed/27608845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11868
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