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Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia
In lymphoid organs, nurse-like cells (NLCs) show properties of tumor-associated macrophages, playing a crucial role in chronic lymphocytic leukemia (CLL) cell survival. Ibrutinib, a potent inhibitor of Bruton's tyrosine kinase (BTK), is able to counteract pro-survival signals in CLL cells. Sinc...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323207/ https://ncbi.nlm.nih.gov/pubmed/27602755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11782 |
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