Leptin promotes migration and invasion of breast cancer cells by stimulating IL-8 production in M2 macrophages

This study aims to investigate the mechanisms underlying leptin-mediated crosstalk between tumor-associated macrophages (M2 macrophages) and breast cancer cells. THP1 human leukemic monocytes were induced to differentiate into M2 macrophages by PMA (100 nM) and IL-4 (20 ng/mL). Quantitative RT-PCR a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cao, Hong, Huang, Yunxiu, Wang, Lin, Wang, Hong, Pang, Xueli, Li, Kuangfa, Dang, Weiqi, Tang, Hao, Wei, Lan, Su, Min, Tang, Cuiping, Chen, Tingmei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323167/
https://ncbi.nlm.nih.gov/pubmed/27588409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11761
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