HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

HuR is an mRNA-binding protein whose overexpression in cancer cells has been associated with poor prognosis and resistance to therapy. While reports on HuR overexpression contributing to chemoresistance exist, limited information is available on HuR and radioresistance especially in triple-negative...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Mehta, Meghna, Basalingappa, Kanthesh, Griffith, James N., Andrade, Daniel, Babu, Anish, Amreddy, Narsireddy, Muralidharan, Ranganayaki, Gorospe, Myriam, Herman, Terence, Ding, Wei-Qun, Ramesh, Rajagopal, Munshi, Anupama
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323119/
https://ncbi.nlm.nih.gov/pubmed/27588488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11706
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk