HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

HuR is an mRNA-binding protein whose overexpression in cancer cells has been associated with poor prognosis and resistance to therapy. While reports on HuR overexpression contributing to chemoresistance exist, limited information is available on HuR and radioresistance especially in triple-negative...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Mehta, Meghna, Basalingappa, Kanthesh, Griffith, James N., Andrade, Daniel, Babu, Anish, Amreddy, Narsireddy, Muralidharan, Ranganayaki, Gorospe, Myriam, Herman, Terence, Ding, Wei-Qun, Ramesh, Rajagopal, Munshi, Anupama
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323119/
https://ncbi.nlm.nih.gov/pubmed/27588488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11706
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