HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

HuR is an mRNA-binding protein whose overexpression in cancer cells has been associated with poor prognosis and resistance to therapy. While reports on HuR overexpression contributing to chemoresistance exist, limited information is available on HuR and radioresistance especially in triple-negative...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Mehta, Meghna, Basalingappa, Kanthesh, Griffith, James N., Andrade, Daniel, Babu, Anish, Amreddy, Narsireddy, Muralidharan, Ranganayaki, Gorospe, Myriam, Herman, Terence, Ding, Wei-Qun, Ramesh, Rajagopal, Munshi, Anupama
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323119/
https://ncbi.nlm.nih.gov/pubmed/27588488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11706
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