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Biochemical Characterization of a Eukaryotic Decalin-Forming Diels–Alderase

The trans-decalin structure formed as a result of intramolecular Diels–Alder cycloaddition is widely present among bioactive natural products isolated from fungi. In this work, we elucidated the concise, three-enzyme biosynthetic pathway of the cytotoxic myceliothermophin and biochemically character...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Li, Li, Yu, Peiyuan, Tang, Man-Cheng, Zou, Yi, Gao, Shu-Shan, Hung, Yiu-Sun, Zhao, Muxun, Watanabe, Kenji, Houk, K. N., Tang, Yi
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323083/
https://ncbi.nlm.nih.gov/pubmed/27960349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10452
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