Expression of glyoxalase-I is reduced in cirrhotic livers: A possible mechanism in the development of cirrhosis

BACKGROUND: High concentrations of methylglyoxal (MGO) cause cytotoxiticy via formation of advanced glycation endproducts (AGEs) and inflammation. MGO is detoxificated enzymatically by glyoxalase-I (Glo-I). The aim of this study was to analyze the role of Glo-I during the development of cirrhosis. M...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Hollenbach, Marcus, Thonig, Antje, Pohl, Sabine, Ripoll, Cristina, Michel, Maurice, Zipprich, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322979/
https://ncbi.nlm.nih.gov/pubmed/28231326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171260
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk