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Effects of Na(+) channel blockers on the restitution of refractory period, conduction time, and excitation wavelength in perfused guinea-pig heart
Na(+) channel blockers flecainide and quinidine can increase propensity to ventricular tachyarrhythmia, whereas lidocaine and mexiletine are recognized as safe antiarrhythmics. Clinically, ventricular fibrillation is often precipitated by transient tachycardia that reduces action potential duration,...
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| Publicado no: | PLoS One |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5322976/ https://ncbi.nlm.nih.gov/pubmed/28231318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172683 |
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