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Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups

Medulloblastoma comprises four main subgroups (WNT, SHH, Group 3 and Group 4) originally defined by transcriptional profiling. In primary medulloblastoma tissues, these groups are thought to be distinguishable using the immunohistochemical detection of β-catenin, filamin A, GAB1 and YAP1 protein mar...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Chlapek, Petr, Zitterbart, Karel, Kren, Leos, Filipova, Lenka, Sterba, Jaroslav, Veselska, Renata
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322931/
https://ncbi.nlm.nih.gov/pubmed/28231263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172552
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