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Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a

The live oral typhoid vaccine Ty21a elicits predominantly CD8+, as well as CD4+ T cells mediated immune responses. Clinical field studies showed that Ty21a is moderately effective against S. Typhi and S. Paratyphi B, but not S. Paratyphi A infections. In this study we describe the in depth character...

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Dettagli Bibliografici
Pubblicato in:Clin Immunol
Autori principali: Wahid, Rezwanul, Fresnay, Stephanie, Levine, Myron M., Sztein, Marcelo B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322816/
https://ncbi.nlm.nih.gov/pubmed/27634430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2016.09.006
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