Driver mutations (JAK2V617F, MPLW515L/K or CALR), pentraxin-3 and C-reactive protein in essential thrombocythemia and polycythemia vera

BACKGROUND: The driver mutations JAK2V617F, MPLW515L/K and CALR influence disease phenotype of myeloproliferative neoplasms (MPNs) and might sustain a condition of chronic inflammation. Pentraxin 3 (PTX3) and high-sensitivity C-reactive protein (hs-CRP) are inflammatory biomarkers potentially useful...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Lussana, Federico, Carobbio, Alessandra, Salmoiraghi, Silvia, Guglielmelli, Paola, Vannucchi, Alessandro Maria, Bottazzi, Barbara, Leone, Roberto, Mantovani, Alberto, Barbui, Tiziano, Rambaldi, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322581/
https://ncbi.nlm.nih.gov/pubmed/28228104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0425-z
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