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Oxygen impairs oligodendroglial development via oxidative stress and reduced expression of HIF-1α
The premature increase of oxygen tension may contribute to oligodendroglial precursor cell (OPC) damage in preterm infants. Fetal OPCs are exposed to low oxygen tissue tensions not matched when cells are cultured in room air. Maturation (A2B5, O4, O1, MBP, CNP, arborization), oxidative stress (nitro...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5322337/ https://ncbi.nlm.nih.gov/pubmed/28230075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43000 |
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