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Endogenous Leucine-Rich Repeat Kinase 2 Slows Synaptic Vesicle Recycling in Striatal Neurons

Dominant mutations in leucine-rich repeat kinase 2 (LRRK2) produce the most common inherited form of Parkinson’s disease (PD) but the function of LRRK2 remains poorly understood. The presynaptic role of multiple genes linked to PD including α-synuclein (α-syn) has suggested that LRRK2 may also influ...

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Bibliografski detalji
Izdano u:Front Synaptic Neurosci
Glavni autori: Maas, James W. Jr., Yang, Jing, Edwards, Robert H.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322269/
https://ncbi.nlm.nih.gov/pubmed/28280464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2017.00005
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