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Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins

Clostridium botulinum neurotoxins (BoNTs) are the most poisonous naturally occurring protein toxins known to mankind and are the causative agents of the severe and potentially life-threatening disease botulism. They are also known for their application as cosmetics and as unique bio-pharmaceuticals...

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Vydáno v:Front Pharmacol
Hlavní autoři: Jenkinson, Stephen P., Grandgirard, Denis, Heidemann, Martina, Tscherter, Anne, Avondet, Marc-André, Leib, Stephen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322221/
https://ncbi.nlm.nih.gov/pubmed/28280466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00073
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