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Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas.

T-cell lymphomas induced by Moloney murine leukemia virus frequently have proviruses integrated at the Mlvi-4 and Mlvi-1 loci, which map approximately 30 and 270 kilobases 3' of the promoter region of the Myc protooncogene, respectively. Provirus insertion in these loci is responsible for the activa...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lazo, P A, Lee, J S, Tsichlis, P N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53222/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688653/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.170
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