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Strategies to Inhibit Myc and Their Clinical Applicability

Myc is an oncogene deregulated in most—perhaps all—human cancers. Each Myc family member, c-, L-, and N-Myc, has been connected to tumor progression and maintenance. Myc is recognized as a “most wanted” target for cancer therapy, but has for many years been considered undruggable, mainly due to its...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Whitfield, Jonathan R., Beaulieu, Marie-Eve, Soucek, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322154/
https://ncbi.nlm.nih.gov/pubmed/28280720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00010
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