Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies.
P-glycoprotein is a highly conserved membrane protein shown to be overexpressed in many multidrug-resistant tumor cell lines. P-glycoprotein is encoded by a small gene family in mammalian cells. Class I and II isoforms cause multidrug resistance, whereas class III does not. In this report, we have c...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.152 |
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