Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation

Previous studies have revealed that nucleosomes impede elongation of RNA polymerase II (RNAPII). Recent observations suggest a role for ATP-dependent chromatin remodellers in modulating this process, but direct in vivo evidence for this is unknown. Here using fission yeast, we identify Fun30(Fft3) a...

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Udgivet i:Nat Commun
Main Authors: Lee, Junwoo, Shik Choi, Eun, David Seo, Hogyu, Kang, Keunsoo, Gilmore, Joshua M., Florens, Laurence, Washburn, Michael P., Choe, Joonho, Workman, Jerry L., Lee, Daeyoup
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321744/
https://ncbi.nlm.nih.gov/pubmed/28218250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14527
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