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Primary Brain Calcification Causal PiT2 Transport-Knockout Variants can Exert Dominant Negative Effects on Wild-Type PiT2 Transport Function in Mammalian Cells

Primary brain calcification (PBC) is a neurodegenerative disorder characterized by calcium-phosphate deposits in the basal ganglia and often also other areas of the brain. The prevalent clinical manifestations are cognitive impairment, neuropsychiatric symptoms, and movement disorders. In recent yea...

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Detalhes bibliográficos
Publicado no:J Mol Neurosci
Main Authors: Larsen, Frederik Tibert, Jensen, Nina, Autzen, Jacob Kwasi, Kongsfelt, Iben Boutrup, Pedersen, Lene
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321689/
https://ncbi.nlm.nih.gov/pubmed/27943094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-016-0868-7
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