Pharmacokinetic modeling of [(11)C]flumazenil kinetics in the rat brain

BACKGROUND: Preferred models for the pharmacokinetic analysis of [(11)C]flumazenil human studies have been previously established. However, direct translation of these models and settings to animal studies might be sub-optimal. Therefore, this study evaluates pharmacokinetic models for the quantific...

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Bibliografiska uppgifter
I publikationen:EJNMMI Res
Huvudupphovsmän: Lopes Alves, Isadora, Vállez García, David, Parente, Andrea, Doorduin, Janine, Dierckx, Rudi, Marques da Silva, Ana Maria, Koole, Michel, Willemsen, Antoon, Boellaard, Ronald
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321646/
https://ncbi.nlm.nih.gov/pubmed/28229437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0265-4
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