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Pasteurella multocida toxin: potent mitogen for cultured fibroblasts.

Native Pasteurella multocida toxin (PMT) is shown to be an extremely potent mitogen for Swiss 3T3 fibroblasts. Half-maximal stimulation of DNA synthesis was obtained at concentrations of 1 and 2 pM for recombinant PMT (rPMT) and PMT, respectively. The degree of rPMT-induced DNA synthesis was compara...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Rozengurt, E, Higgins, T, Chanter, N, Lax, A J, Staddon, J M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53212/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153282/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.123
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