Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group

PURPOSE: This retrospective cohort study aimed to determine the predictive relevance of clinical characteristics, additional cytogenetic aberrations, and cKIT and RAS mutations, as well as to evaluate whether specific treatment elements were associated with outcomes in pediatric t(8;21)-positive pat...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Klein, Kim, Kaspers, Gertjan, Harrison, Christine J., Beverloo, H. Berna, Reedijk, Ardine, Bongers, Mathilda, Cloos, Jacqueline, Pession, Andrea, Reinhardt, Dirk, Zimmerman, Martin, Creutzig, Ursula, Dworzak, Michael, Alonzo, Todd, Johnston, Donna, Hirsch, Betsy, Zapotocky, Michal, De Moerloose, Barbara, Fynn, Alcira, Lee, Vincent, Taga, Takashi, Tawa, Akio, Auvrignon, Anne, Zeller, Bernward, Forestier, Erik, Salgado, Carmen, Balwierz, Walentyna, Popa, Alexander, Rubnitz, Jeffrey, Raimondi, Susana, Gibson, Brenda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321085/
https://ncbi.nlm.nih.gov/pubmed/26573082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.61.1947
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