Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group

PURPOSE: This retrospective cohort study aimed to determine the predictive relevance of clinical characteristics, additional cytogenetic aberrations, and cKIT and RAS mutations, as well as to evaluate whether specific treatment elements were associated with outcomes in pediatric t(8;21)-positive pat...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: Klein, Kim, Kaspers, Gertjan, Harrison, Christine J., Beverloo, H. Berna, Reedijk, Ardine, Bongers, Mathilda, Cloos, Jacqueline, Pession, Andrea, Reinhardt, Dirk, Zimmerman, Martin, Creutzig, Ursula, Dworzak, Michael, Alonzo, Todd, Johnston, Donna, Hirsch, Betsy, Zapotocky, Michal, De Moerloose, Barbara, Fynn, Alcira, Lee, Vincent, Taga, Takashi, Tawa, Akio, Auvrignon, Anne, Zeller, Bernward, Forestier, Erik, Salgado, Carmen, Balwierz, Walentyna, Popa, Alexander, Rubnitz, Jeffrey, Raimondi, Susana, Gibson, Brenda
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321085/
https://ncbi.nlm.nih.gov/pubmed/26573082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.61.1947
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