Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus

The increased expression of genes induced by type I interferon (IFN) is characteristic of viral infections and systemic lupus erythematosus (SLE). We showed that mitochondrial antiviral signaling (MAVS) protein, which normally forms a complex with retinoic acid gene I (RIG-I)–like helicases during v...

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發表在:Sci Signal
Main Authors: Buskiewicz, Iwona A., Montgomery, Theresa, Yasewicz, Elizabeth C., Huber, Sally A., Murphy, Michael P., Hartley, Richard C., Kelly, Ryan, Crow, Mary K., Perl, Andras, Budd, Ralph C., Koenig, Andreas
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321043/
https://ncbi.nlm.nih.gov/pubmed/27899525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf1933
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