Differentiation of human telencephalic progenitor cells into MSNs by inducible expression of Gsx2 and Ebf1

Medium spiny neurons (MSNs) are a key population in the basal ganglia network, and their degeneration causes a severe neurodegenerative disorder, Huntington's disease. Understanding how ventral neuroepithelial progenitors differentiate into MSNs is critical for regenerative medicine to develop...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Faedo, Andrea, Laporta, Angela, Segnali, Alice, Galimberti, Maura, Besusso, Dario, Cesana, Elisabetta, Belloli, Sara, Moresco, Rosa Maria, Tropiano, Marta, Fucà, Elisa, Wild, Stefan, Bosio, Andreas, Vercelli, Alessandro E., Biella, Gerardo, Cattaneo, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321017/
https://ncbi.nlm.nih.gov/pubmed/28137879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611473114
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