An inherited genetic variant in CEP72 promoter predisposes to vincristine-induced peripheral neuropathy in adults with acute lymphoblastic leukemia

Peripheral neuropathy is a major toxicity of vincristine, yet no strategies exist for identifying at-risk adult patients. We used a case-control design of 48 adults receiving protocol therapy for acute lymphoblastic leukemia (ALL) who developed vincristine-induced neuropathy (NCI Grade 2-4) during t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Pharmacol Ther
Egile Nagusiak: Stock, Wendy, Diouf, Barthelemy, Crews, Kristine R., Pei, Deqing, Cheng, Cheng, Laumann, Kristina, Mandrekar, Sumithra J., Luger, Selina, Advani, Anjali, Stone, Richard M., Larson, Richard A., Evans, William E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320866/
https://ncbi.nlm.nih.gov/pubmed/27618250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.506
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