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Effects of Valproic Acid on Radiation-Induced Chromosomal Aberrations in Human Lymphocytes

One of the most widely employed histone deacetylases inhibitors in the clinic is the valproic acid (VA), proving to have a good tolerance and low side effects on human health. VA induces changes in chromatin structure making DNA more susceptible to damage induction and influence DNA repair efficienc...

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Publicado en:Genome Integr
Autores principales: Di Tomaso, María Vittoria, Gregoire, Eric, Martínez-López, Wilner
Formato: Artigo
Lenguaje:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320781/
https://ncbi.nlm.nih.gov/pubmed/28250911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2041-9414.198909
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