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High mutation rates explain low population genetic divergence at copy-number-variable loci in Homo sapiens

Copy-number-variable (CNV) loci differ from single nucleotide polymorphic (SNP) sites in size, mutation rate, and mechanisms of maintenance in natural populations. It is therefore hypothesized that population genetic divergence at CNV loci will differ from that found at SNP sites. Here, we test this...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hu, Xin-Sheng, Yeh, Francis C., Hu, Yang, Deng, Li-Ting, Ennos, Richard A., Chen, Xiaoyang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320550/
https://ncbi.nlm.nih.gov/pubmed/28225073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43178
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