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Rapid and Reliable Detection of Nonsyndromic Hearing Loss Mutations by Multicolor Melting Curve Analysis

Hearing loss is a common birth defect worldwide. The GJB2, SLC26A4, MT-RNR1 and MT-TS1 genes have been reported as major pathogenic genes in nonsyndromic hearing loss. Early genetic screening is recommended to minimize the incidence of hearing loss. We hereby described a multicolor melting curve ana...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Xudong, Hong, Yongjun, Cai, Peihong, Tang, Ning, Chen, Ying, Yan, Tizhen, Liu, Yinghua, Huang, Qiuying, Li, Qingge
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320477/
https://ncbi.nlm.nih.gov/pubmed/28225033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42894
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