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Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni.

Eosinophils are thought to play a major role in the immunobiology of schistosomiasis. To investigate the immunologic basis of the eosinophil response and directly assess the function of eosinophils in egg-induced pathology, mice infected with Schistosoma mansoni were injected with a monoclonal antib...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Sher, A, Coffman, R L, Hieny, S, Scott, P, Cheever, A W
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2104985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.61
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