RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling

OBJECTIVE: Epidermal stem cells (ESCs) play a critical role in wound healing, but the mechanism underlying ESC proliferation is not well defined. Here, we explore the effects of RhoA on ESC proliferation and the possible underlying mechanism. METHODS: Human ESCs were enriched by rapid adhesion to co...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Fan, Zhan, Rixing, Chen, Liang, Dai, Xia, Wang, Wenping, Guo, Rui, Li, Xiaoge, Li, Zhe, Wang, Liang, Huang, Shupeng, Shen, Jie, Li, Shirong, Cao, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319766/
https://ncbi.nlm.nih.gov/pubmed/28222172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172613
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