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How important is thermodynamics for identifying elementary flux modes?
We present a method for computing thermodynamically feasible elementary flux modes (tEFMs) using equilibrium constants without need of internal metabolite concentrations. The method is compared with the method based on a binary distinction between reversible and irreversible reactions. When all reac...
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Publicado no: | PLoS One |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319754/ https://ncbi.nlm.nih.gov/pubmed/28222104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171440 |
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