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Design features for optimization of tetrapyrrole macrocycles as antimicrobial and anticancer photosensitizers

Photodynamic therapy (PDT) uses non-toxic dyes called photosensitizers (PS) and harmless visible light that combine to form highly-toxic reactive oxygen species that kill cells. Originally a cancer therapy, PDT now includes applications for infections. The most widely studied PS are tetrapyrrole mac...

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Detalhes bibliográficos
Publicado no:Chem Biol Drug Des
Main Authors: De Pinillos Bayona, Alejandra Martinez, Mroz, Pawel, Thunshelle, Connor, Hamblin, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319686/
https://ncbi.nlm.nih.gov/pubmed/28205400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12792
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