Retinoic acid promotes expression of germline-specific genes in chicken blastoderm cells by stimulating Smad1/5 phosphorylation in a feeder-free culture system

BACKGROUND: Producing transgenic chickens with chicken blastodermal cells (cBCs) is inefficient due to the extremely low germline transmission capacity of cBCs. As chicken primordial germ cells (PGCs) have been reported as an efficient method for producing transgenic chickens, the inefficiency of cB...

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Foilsithe in:BMC Biotechnol
Main Authors: Tang, Xiaochuan, Xu, Shiyong, Zhang, Hongpeng, Chen, Qing, Li, Rongyang, Wu, Wangjun, Yu, Minli, Liu, Honglin
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319176/
https://ncbi.nlm.nih.gov/pubmed/28219352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0332-y
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