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Regulation of voltage-gated potassium channels attenuates resistance of side-population cells to gefitinib in the human lung cancer cell line NCI-H460

BACKGROUND: Side-population (SP) cells that exclude anti-cancer drugs have been found in various tumor cell lines. Moreover, SP cells have a higher proliferative potential and drug resistance than main population cells (Non-SP cells). Also, several ion channels are responsible for the drug resistanc...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Choi, Seon Young, Kim, Hang-Rae, Ryu, Pan Dong, Lee, So Yeong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319158/
https://ncbi.nlm.nih.gov/pubmed/28219421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0118-9
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